Hemp has at times in the past been grown simply for its ornamental value. The short, strongly-branched cultivar ‘Panorama’ (Fig. 43) bred by Iván Bósca, the dean of the world’s living hemp breeders, was commercialized in Hungary in the 1980s, and has been said to be the only ornamental hemp cultivar available. It has had limited success, of course, because there are very few circumstances that permit private gardeners can grow Cannabis as an ornamental today. By contrast, beautiful ornamental cultivars of opium poppy are widely cultivated in home gardens across North America, despite their absolute illegality and the potentially draconian penalties that could be imposed. Doubtless in the unlikely event that it became possible, many would grow hemp as an ornamental.
The most valid claims to environmental friendliness of hemp are with respect to agricultural biocides (pesticides, fungicides, herbicides). Cannabis sativa is known to be exceptionally resistant to pests (Fig. 51), although, the degree of immunity to attacking organisms has been greatly exaggerated, with several insects and fungi specializing on hemp. Despite this, use of pesticides and fungicides on hemp is usually unnecessary, although introduction of hemp to regions should be expected to generate local problems. Cannabis sativa is also relatively resistant to weeds, and so usually requires relatively little herbicide. Fields intended for hemp use are still frequently normally cleared of weeds using herbicides, but so long as hemp is thickly seeded (as is always done when hemp is grown for fiber), the rapidly developing young plants normally shade out competing weeds.

You want to make sure that your pet has only the best, and that’s why we make it so easy and convenient to shop for dogs and other products through the American Hemp Oil website or on the phone with one of our helpful representatives. Your order will be shipped right to your front door, so your pet can get back to feeling better as soon as possible.
Cannabis sativa is an annual wind-pollinated plant, normally dioecious and dimorphic, although sometimes monoecious (mostly in several modern European fiber cultivars). Figure 2 presents the basic morphology of the species. Some special hybrids, obtained by pollinating females of dioecious lines with pollen from monoecious plants, are predominantly female (so-called “all-female,” these generally also produce some hermaphrodites and occasional males). All-female lines are productive for some purposes (e.g. they are very uniform, and with very few males to take up space they can produce considerable grain), but the hybrid seed is expensive to produce. Staminate or “male” plants tend to be 10%–15% taller and are less robust than the pistillate or “female” (note the comparatively frail male in Fig. 3). So prolific is pollen production that an isolation distance of about 5 km is usually recommended for generating pure-bred foundation seed. A “perigonal bract” subtends each female flower, and grows to envelop the fruit. While small, secretory, resin-producing glands occur on the epidermis of most of the above-ground parts of the plant, the glands are very dense and productive on the perigonal bracts, which are accordingly of central interest in marijuana varieties. The root is a laterally branched taproot, generally 30–60 cm deep, up to 2.5 m in loose soils, very near the surface and more branched in wet soils. Extensive root systems are key to the ability of hemp crops to exploit deep supplies of nutrients and water. The stems are erect, furrowed, and usually branched, with a woody interior, and may be hollow in the internodes. Although the stem is often woody, the species is frequently referred to as a herb or forb. Plants vary enormously in height depending on genetic constitution and environment (Fig. 4), but are typically 1–5 m (heights of 12 m or more in cultivation have been claimed).
While CBD can be extracted from non-hemp varieties of the plant, hemp-derived CBD is less restricted by the government because of its inherently low levels of THC. CBD from hemp is legal for sale in most US states, while CBD products derived from non-hemp varieties can contain noticeable amounts of THC, and are therefore subject to stricter laws and regulations.
The cool thing is that humans are not the only species known to have this Endocannabinoid system. Many species have been shown in research to have these receptors that cannabinoids have an effect too. One of the more popular researched species is dogs who have been shown to have positive reactions to medical marijuana but THC can be toxic for, this is a place for CBD oil for dogs to shine.
This is the story of our 5 year old Charlotte Figi. Charlotte suffered from Dravet Syndrome, a severe form of epilepsy found in children. From the time she was 2 she was having over 300 seizures a week which drastically affected her ability to learn, speak or even walk. She was unable to keep up with her twin sister. She was catatonic and nothing the doctors could do for her helped. All of their “medicines” had no effect on her condition and if anything they made her worse. Some of them almost killing her.After exhausting all other treatments, her we turned to the internet to see what alternative treatments may be available. To our surprise we found a certain strain of cannabis from Dr MARK DONALD (the strain was later named Charlottes Web in her honor) was specifically helping children with Dravet Syndrome. So we made the decision to give cannabis oil to Charlotte and from the first dose we noticed results. The 300+ seizures she was experiencing each week was reduced to only 1. we have been amazed with the results and are so happy to get our daughter back . All thanks goes to Dr Mark Donald for providing us with the Cannabis Oil. WE VOTE FOR DR MARK DONALD 100%
Cooper recently got funding from the National Institutes of Health for a study looking at cannabinoids — including CBD in isolation — as a substitute for opioids, and numerous other clinical trials of CBD are underway. It will be several years before results are available, but these studies should help clarify both what benefits the substance may provide and any side effects it may come with. Most of the adverse effects so far associated with cannabis, such as impairments in short-term memory, coordination and judgment,2 come from products that contain THC as well as CBD, Cooper said, but we need to do more studies to find out for sure whether CBD has fewer risks. Studies are also needed to identify the best way to administer and dose CBD. “I get emails from people asking me what dose of CBD to use, and the truth is, we really don’t know,” Cooper said.
If your pet is suffering from any of the above conditions, CBD is a no-brainer. While traditional methods can involve giving your dog synthetic medications, CBD provides an all-natural alternative to treating your dog’s conditions. And because CBD is very diverse, there are many different ways to easily treat your dog with CBD, such as giving your dog a CBD dog treat, adding CBD oil to their food, or adding water-soluble CBD to their water. Just add in CBD to what you’re already doing, and help promote a healthy lifestyle for your best bud!
Cannabis use is associated with increased recruitment of task-related areas, such as the dorsolateral prefrontal cortex, which is thought to reflect compensatory activity due to reduced processing efficiency.[114][113][116] Cannabis use is also associated with downregulation of CB1 receptors. The magnitude of down regulation is associated with cumulative cannabis exposure, and is reversed after one month of abstinence.[117][118][119] There is limited evidence that chronic cannabis use can reduce levels of glutamate metabolites in the human brain.[120]
After a recent running injury, my right hip flexor has been incredibly tight. I have been going to weekly sports therapy, which is working well. To aid in relaxing my leg, I use the pain cream every morning and night. I feel like it unlocks my leg and the range of motion improves dramatically. My only wish is that it would last longer so I only had to apply once a day!

The cool thing is that humans are not the only species known to have this Endocannabinoid system. Many species have been shown in research to have these receptors that cannabinoids have an effect too. One of the more popular researched species is dogs who have been shown to have positive reactions to medical marijuana but THC can be toxic for, this is a place for CBD oil for dogs to shine.
If you haven’t been bombarded with CBD marketing or raves about it from friends, get ready. This extract—which comes from either marijuana or its industrial cousin, hemp—is popping up everywhere. There are CBD capsules, tinctures, and liquids for vaping plus CBD-infused lotions, beauty products, snacks, coffee, and even vaginal suppositories. Already some 1,000 brands of CBD products are available in stores—and online in states that don’t have lenient cannabis laws. This is a tiny fraction of what’s to come: The CBD market is poised to exceed $1 billion by 2020, per the Chicago-based research firm Brightfield Group.
Hemp, or industrial hemp (from Old English hænep),[1] typically found in the northern hemisphere, is a variety of the Cannabis sativa plant species that is grown specifically for the industrial uses of its derived products.[2] It is one of the fastest growing plants[3] and was one of the first plants to be spun into usable fiber 10,000 years ago.[4] It can be refined into a variety of commercial items including paper, textiles, clothing, biodegradable plastics, paint, insulation, biofuel, food, and animal feed.[5]
Understanding CBD’s neurological effects is a complicated business, because of the wide variety of receptors with which it interacts.  But that complexity may be the key to its promise as a therapeutic agent. Motivational disorders like addiction and anxiety are themselves highly complex; they arise from incompletely understood causes that span multiple receptor systems and neural networks in the brain. CBD’s complex, multi-target effects may therefore be crucial to its potential for aiding the treatment of such disorders. Over the coming years, researchers will continue to further understand this complexity and uncover the full scope of CBD’s therapeutic potential.
Understanding CBD’s analgesic, or pain-relieving, interactions with the ECS can shed light on CBD’s other interactions and effects. Importantly, the ECS participates in our bodies’ pain processing, but when CBD is introduced to our ECS, it stops the body from absorbing a pain-regulating compound known as anandamide — one of our body’s’ own natural cannabinoid molecules. Inhibiting the absorption of this compound shunts excess quantities into the bloodstream that in turn reduces pain. One study has revealed that CBD targets alpha-3 (α3) glycine receptors to suppress chronic pain and inflammation associated with dysfunctional glycine receptors, which are an important target for pain processing in the spine. In both humans and animal models, CBD has been shown to have a variety of anti-inflammatory properties.
Although still considered to be quite controversial, a growing number of pet owners are discovering the benefits of CBD for dogs, especially their chronically ill companions. In this article I'll introduce you to some of the proven and assumed health benefits of CBD oil for dogs so that you can decide for yourself if this is right for your pooch or not.
Life-threatening risks for dogs from medical cannabis are “exceedingly rare,” Richter says, adding that toxicity more often occurs when a pet has eaten a product that contains chocolate, coffee, or raisins. “Even if the THC toxicity is not excessive, they can sometimes have problems due to these other ingredients.” That said, ingestion of large amounts of marijuana has been fatal in a number of dogs, so preventing overdoses with medical cannabis is still extremely important, warns Dr. Jennifer Coates, a veterinary advisor with petMD.
By the 1930s, marijuana was banned in 24 states. The newly minted Federal Bureau of Narcotics launched a campaign against the drug, and newspapers fueled hysteria with headlines like the 1933 Los Angeles Examiner's "Murder Weed Found Up and Down the Coast — Deadly Marihuana Dope Plant Ready for Harvest That Means Enslavement of California Children." By 1937, Congress passed the Marihuana Tax Act, which effectively banned marijuana except for a few medicinal purposes, according to "Smoke Signals: A Social History of Marijuana – Medical, Recreational and Legal" (Scribner, 2012).

Toronto, Ontario--(Newsfile Corp. - February 28, 2019) - Gunpowder Capital Corp., (CSE: GPC), (CSE: GPC.PR.A), (OTCQB: GNPWF), (FSE: YS6N), ("Gunpowder" or the "Corporation") is very pleased to announce that it has entered into a strategic relationship with Hemp Inc., (OTC Pink: HEMP) of Las Vegas Nevada with the purpose of entering into the Industrial Hemp industry in the United States.Under the terms of the agreement, Hemp Inc., and Gunpowder will both make strategic ...
I was in a car accident several years ago I have tried everything to help relieve the pain in my back due to the accident nothing has worked! I picked this up thinking I would give it a shot and fell in love it worked wonders and everyone in my house now uses this from my diabetic son to my mother. Thank you for actually having a product that does what it says!! I feel like the old me now
• Speaking of which: Has it been third-party tested? Nearly every expert Health spoke to agreed that your CBD products should be tested by a third party to confirm the label's accuracy. This is a real concern in the industry—take the 2017 Journal of the American Medical Association study, for example, which tested 84 CBD products and found that 26% contained lower doses than stated on the bottle. Look for a quality assurance stamp or certificate of analysis from a third party (aka not the actual brand) or check the retailer's website if you don't see it on the product's label.
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.
There are also other difficulties in researching the effects of cannabis. Many people who smoke cannabis also smoke tobacco.[277] This causes confounding factors, where questions arise as to whether the tobacco, the cannabis, or both that have caused a cancer. Another difficulty researchers have is in recruiting people who smoke cannabis into studies. Because cannabis is an illegal drug in many countries, people may be reluctant to take part in research, and if they do agree to take part, they may not say how much cannabis they actually smoke.[278]
I was originally prescribed this as part of my protocol to help with my Hashimoto’s, but I find it to be awesome for joint and muscle pain from injury as well. It is great for dry skin, too, shea butter is so soothing. I especially appreciate the ingredients – no preservatives, or fragrance chemicals, just good simple stuff. Keep up the good work and thank you!
When privacy isn’t a requirement, outdoor cannabis grows can provide many advantages over indoor operations. Sunlight is the single most important factor for successful outdoor marijuana growing. It’s important to choose a plot with total sunshine throughout the day. Therefore, cannabis growers in the northern hemisphere will want plots with southern exposure, exposing marijuana plants to the sun’s arc across the sky.

Hemp includes all varieties of the Cannabis genus that contain negligible amounts of THC, the chemical that makes marijuana psychoactive and gets you “high”.  The Cannabis family has several different breeds, yet it is most infamously known for marijuana (“weed”). This is the main reason why people confuse the term hemp with marijuana. Hemp actually refers to the industrial, non-drug variant that is cultivated for its fiber, hurd, and seeds.
Phytocannabinoids are the herbal, natural and classical cannabinoids found in the cannabis plant. The glandular structure called the trichomes is where the concentrated viscous resin of the plant is found. There are over 60 cannabinoids that have been isolated from the plant. Tetrahydracannabinol (THC), Cannabidiol (CBD) and Cannabinol (CBN) are the most prevalent ones and have also been the most studied. Cannabidiol (CBD) accounts for up to 40% of the plant’s extract. It has been widely reported that CBD offers the greatest possible benefits of any of the extracts found in the plant. CBD can also be derived from hemp. Hemp and cannabis both contain large amounts of natural CBD, but hemp is naturally low in THC; thus, making it easier for manufacturers to create high CBD-infused products with low to non-existent THC levels. Since THC is (mostly) still illegal in the United States, most CBD items we carry are derived from hemp. Each CBD product varies in the amount of CBD and THC levels found in the product. No items we carry are over the legal limit of THC levels, which is 0.3%, according to U.S. Federal Law.
Although still considered to be quite controversial, a growing number of pet owners are discovering the benefits of CBD for dogs, especially their chronically ill companions. In this article I'll introduce you to some of the proven and assumed health benefits of CBD oil for dogs so that you can decide for yourself if this is right for your pooch or not.
Sean McAllister, one of the researchers at California Pacific, was studying the effects of Cannabidiol(CBD). Pierre Desprez, a molecular biologist researcher, began studying ID-1, the gene that causes cancer to spread, about 20 years ago. The two combined their research and introduced CBD to cancer cells containing ID-1 in a petri dish. They found that CBD stopped the metastasis of the cancer cells.
What exactly is cannabidiol (CBD) and more importantly, what does it do? Those questions and more are at the heart of this comprehensive guide to one of the most fascinating and important compounds of the cannabis plant. Cannabis plants are chemical powerhouses that produce more than 400 different compounds. Not all of those compounds are unique to marijuana, of course, and appear in many other species of plants. That’s why marijuana can smell like pine trees or taste like fresh lemons. But of those 400 compounds, more than 60 of them are totally specific to the plant genus Cannabis. Scientists call these special compounds “cannabinoids.” However, not all cannabinoids are created equal. One of them, cannabidiol, or CBD, holds the key to the wide variety of medicinal and therapeutic effects marijuana offers.
In Western Europe, the cultivation of hemp was not legally banned by the 1930s, but the commercial cultivation stopped by then, due to decreased demand compared to increasingly popular artificial fibers.[148] Speculation about the potential for commercial cultivation of hemp in large quantities has been criticized due to successful competition from other fibers for many products. The world production of hemp fiber fell from over 300,000 metric tons 1961 to about 75,000 metric tons in the early 1990s and has after that been stable at that level.[149]
In 1976, Canadian botanist Ernest Small[66] and American taxonomist Arthur Cronquist published a taxonomic revision that recognizes a single species of Cannabis with two subspecies: C. sativa L. subsp. sativa, and C. sativa L. subsp. indica (Lam.) Small & Cronq.[62] The authors hypothesized that the two subspecies diverged primarily as a result of human selection; C. sativa subsp. sativa was presumably selected for traits that enhance fiber or seed production, whereas C. sativa subsp. indica was primarily selected for drug production. Within these two subspecies, Small and Cronquist described C. sativa L. subsp. sativa var. spontanea Vav. as a wild or escaped variety of low-intoxicant Cannabis, and C. sativa subsp. indica var. kafiristanica (Vav.) Small & Cronq. as a wild or escaped variety of the high-intoxicant type. This classification was based on several factors including interfertility, chromosome uniformity, chemotype, and numerical analysis of phenotypic characters.[52][62][67]

While CBD can be extracted from non-hemp varieties of the plant, hemp-derived CBD is less restricted by the government because of its inherently low levels of THC. CBD from hemp is legal for sale in most US states, while CBD products derived from non-hemp varieties can contain noticeable amounts of THC, and are therefore subject to stricter laws and regulations.
Finally, the entire marijuana flower structure is coated with resinous crystals called trichomes. Trichomes are translucent, mushroom-like glands that form on the entire flowering structure and even the stems of the marijuana plant. These bulb-shaped glands secrete the rich, aromatic essential oils that give cannabis its smells and flavors. Trichomes also contain cannabinoids.
Jews living in Palestine in the 2nd century were familiar with the cultivation of hemp, as witnessed by a reference to it in the Mishna (Kil'ayim 2:5) as a variety of plant, along with Arum, that sometimes takes as many as three years to grow from a seedling. In late medieval Germany and Italy, hemp was employed in cooked dishes, as filling in pies and tortes, or boiled in a soup.[116] Hemp in later Europe was mainly cultivated for its fibers, and was used for ropes on many ships, including those of Christopher Columbus. The use of hemp as a cloth was centered largely in the countryside, with higher quality textiles being available in the towns.
Will hemp commercial cultivation resume in the US in the foreseeable future? This is difficult to judge, but the following considerations suggest this might occur: (1) increasing awareness of the differences between industrial hemp and marijuana; (2) growing appreciation of the environmental benefits of hemp cultivation; (3) continuing demonstration of successful hemp cultivation and development in most of the remaining western world; all the G8 countries, except the US, produce and export industrial hemp; and (4) increasing pressure on state and federal governments to permit hemp cultivation by farmers, particularly wheat, corn, and tobacco farmers in desperate need of substitute crops, but also for rotation crops to break pest and disease cycles.
The world-leading producer of hemp is China, which produces more than 70% of the world output. France ranks second with about a quarter of the world production. Smaller production occurs in the rest of Europe, Chile, and North Korea. Over 30 countries produce industrial hemp, including Australia, Austria, Canada, Chile, China, Denmark, Egypt, Finland, Germany, Greece,[68] Hungary, India, Italy, Japan, Korea, Netherlands, New Zealand, Poland, Portugal, Romania, Russia, Slovenia, Spain, Sweden, Switzerland, Thailand, Turkey, the United Kingdom and Ukraine.[69][70]
Devinsky puts more weight behind the scientific advancements: In June, the FDA approved an epilepsy drug called Epidiolex, which contains a purified form of CBD oil. In controlled clinical trials, the drug was proven to reduce seizures in people with Dravet syndrome and Lennox-Gastaut syndrome — and it didn't produce as many of the unpleasant side-effects that come with other epilepsy medications.

Our CBD Chew gummies are 100% THC FREE, Vegan, Organic, and NON-GMO! These CBD gummies are a must have when supporting everyday stresses*, support healthy sleep cycles* and support a sense of calm for focus*. With 25mg of CBD in each chew and unique flavors in every jar, you'll never get bored with your FAB CBD gummies. Once you've tried them out, please leave us a CBD gummies review! We'd love to hear from you!
AC/DC: A Sativa-dominant phenotype of Cannatonic, this cultivar boasts one of the highest ratios of CBD to THC, clocking in at 20:1. AC/DC is claimed to help reduce pain, anxiety, depression and migraines while reducing symptoms in patients with epilepsy, some forms of cancer, and multiple sclerosis. This cultivar’s pinene-rich terpene profile offers potent clear-headed pain relief.

In 1972, the Dutch government divided drugs into more- and less-dangerous categories, with cannabis being in the lesser category. Accordingly, possession of 30 grams or less was made a misdemeanor.[214] Cannabis has been available for recreational use in coffee shops since 1976.[215] Cannabis products are only sold openly in certain local "coffeeshops" and possession of up to 5 grams for personal use is decriminalised, however: the police may still confiscate it, which often happens in car checks near the border. Other types of sales and transportation are not permitted, although the general approach toward cannabis was lenient even before official decriminalisation.[216][217][218]

The results of the three large European cohort studies have been confirmed in two smaller New Zealand birth cohorts. Arsenault and colleagues (2002) reported a prospective study of the relationship between adolescent cannabis use and psychosis in a New Zealand birth cohort (n = 759). They found a relationship between cannabis use by age 15 and an increased risk of psychotic symptoms by age 26. The relationship did not change when they controlled for other drug use, but it was no longer statistically significant after adjusting for psychotic symptoms at age 11. The latter probably reflected the small number of psychotic disorders observed in the sample. Fergusson et al. (2003) found a relationship between cannabis dependence at age 18 and later symptoms that included those in the psychotic spectrum reported at age 21 in the Christchurch birth cohort. Fergusson and colleagues adjusted for a large number of potential confounding variables, including self-reported psychotic symptoms at the previous assessment, other drug use and other psychiatric disorders, but whether the association represents a link between cannabis use and psychotic symptoms specifically, or more general psychiatric morbidity, remains unclear.
Hemp fibers are primarily used for textiles, paper, building materials, and other industrial products. Hurds, or shives, are short woody hemp fibers typically found inside the stalk. They’re used to make hempcrete, bedding materials, absorbents, particle board, ceiling panels, compost, and other industrial products. Bast fibers make up the outer portion of the stalk and are typically split into three categories — primary, or line fiber, secondary, and the tow. They are categorized according to their cell strength and cell wall thickness, which will determine the fiber’s strength, durability, and ultimately what the it can be used for.

In the United States, cannabis is overall the number four value crop, and is number one or two in many states including California, New York and Florida, averaging $3,000 per pound ($6,600/kg).[256][257] Some believe it generates an estimated $36 billion market.[258] Some have argued that this estimate is methodologically flawed, and makes unrealistic assumptions about the level of marijuana consumption. Other estimates claiming to correct for this flaw claim that the market is between $2.1-$4.3 billion.[249] The United Nations Office on Drugs and Crime claims in its 2008 World Drug Report that typical U.S. retail prices are $10–15 per gram (approximately $280–420 per ounce). Street prices in North America are known to range from about $40–$400 per ounce ($1.4–$14/g), depending on quality.[259]


The AKC Canine Health Foundation (CHF) is currently sponsoring a study, through the Colorado State University’s College of Veterinary Medicine and Biomedical Sciences, that will evaluate the use of CBD in treatment-resistant epileptic dogs. The CHF hopes that this will be the first study to gain scientific data on the use of CBD in dogs with this condition.
Not until the end of the 20th century was the specific mechanism of action of THC at the neuronal level studied.[citation needed] Researchers have subsequently confirmed that THC exerts its most prominent effects via its actions on two types of cannabinoid receptors, the CB1 receptor and the CB2 receptor, both of which are G protein-coupled receptors.[142] The CB1 receptor is found primarily in the brain as well as in some peripheral tissues, and the CB2 receptor is found primarily in peripheral tissues, but is also expressed in neuroglial cells.[143] THC appears to alter mood and cognition through its agonist actions on the CB1 receptors, which inhibit a secondary messenger system (adenylate cyclase) in a dose-dependent manner. These actions can be blocked by the selective CB1 receptor antagonist rimonabant (SR141716), which has been shown in clinical trials to be an effective treatment for smoking cessation, weight loss, and as a means of controlling or reducing metabolic syndrome risk factors.[144] However, due to the dysphoric effect of CB1 receptor antagonists, this drug is often discontinued due to these side effects.[145]
If your pet is suffering from any of the above conditions, CBD is a no-brainer. While traditional methods can involve giving your dog synthetic medications, CBD provides an all-natural alternative to treating your dog’s conditions. And because CBD is very diverse, there are many different ways to easily treat your dog with CBD, such as giving your dog a CBD dog treat, adding CBD oil to their food, or adding water-soluble CBD to their water. Just add in CBD to what you’re already doing, and help promote a healthy lifestyle for your best bud!
• In 2016, Dr. Stephanie McGrath, neurologist and assistant professor at Colorado State University’s College of Veterinary Medicine & Biomedical Sciences, completed a preliminary pharmacokinetic (what happens to a drug in the body) and safety study on CBD. Following this study, Dr. McGrath began two pilot studies involving owner-enrolled dogs with poorly controlled epilepsy and painful osteoarthritis. These have now ended and results on the epilepsy study are scheduled for publication in the Canadian Veterinary Journal later this year. One of its big-picture findings: 89 percent of dogs who received CBD had a reduction in the frequency of seizures. (McGrath and her team are now starting work on a larger epilepsy-focused project.)
Fortunately for cannabis-curious pet-owners, the spread of legalization across the country is giving doctors enough resources (nerve) to take research into their own hands. In Colorado, Dr. Stephanie McGrath, a neurologist and assistant professor at Colorado State University's College of Veterinary Medicine & Biomedical Sciences, has completed two clinical studies since 2016 on the effects of cannabidiol in dogs with osteoarthritis or epilepsy. In January, the American Kennel Club granted Dr. McGrath $350,000 for her to begin a three-year crossover study of CBD for epilepsy in dogs. Legislation has been proposed in New York and California that would establish guidelines and allow veterinarians to legally discuss the use of cannabis products with their clients.
Research suggests that CBD may exert some of its pharmacological action through its inhibition of fatty acid amide hydrolase (FAAH), which may in turn increase the levels of endocannabinoids, such as anandamide, produced by the body.[7] It has also been speculated that some of the metabolites of CBD have pharmacological effects that contribute to the biological activity of CBD.[39]
In 1924, Russian botanist D.E. Janichevsky concluded that ruderal Cannabis in central Russia is either a variety of C. sativa or a separate species, and proposed C. sativa L. var. ruderalis Janisch, and Cannabis ruderalis Janisch, as alternative names.[48] In 1929, renowned plant explorer Nikolai Vavilov assigned wild or feral populations of Cannabis in Afghanistan to C. indica Lam. var. kafiristanica Vav., and ruderal populations in Europe to C. sativa L. var. spontanea Vav.[53][62] In 1940, Russian botanists Serebriakova and Sizov proposed a complex classification in which they also recognized C. sativa and C. indica as separate species. Within C. sativa they recognized two subspecies: C. sativa L. subsp. culta Serebr. (consisting of cultivated plants), and C. sativa L. subsp. spontanea (Vav.) Serebr. (consisting of wild or feral plants). Serebriakova and Sizov split the two C. sativa subspecies into 13 varieties, including four distinct groups within subspecies culta. However, they did not divide C. indica into subspecies or varieties.[48][64]
According to Delphic analysis by British researchers in 2007, cannabis has a lower risk factor for dependence compared to both nicotine and alcohol.[98] However, everyday use of cannabis may be correlated with psychological withdrawal symptoms, such as irritability or insomnia,[94] and susceptibility to a panic attack may increase as levels of THC metabolites rise.[99][100] However, cannabis withdrawal symptoms are typically mild and are never life-threatening.[101]
Hemp, or industrial hemp (from Old English hænep),[1] typically found in the northern hemisphere, is a variety of the Cannabis sativa plant species that is grown specifically for the industrial uses of its derived products.[2] It is one of the fastest growing plants[3] and was one of the first plants to be spun into usable fiber 10,000 years ago.[4] It can be refined into a variety of commercial items including paper, textiles, clothing, biodegradable plastics, paint, insulation, biofuel, food, and animal feed.[5]
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